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These receptors are involved in the mediation of various physiological processes including sexual desire
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In such cases, higher protein intake (1.0 to 1.2 g/kg/day) is recommended, along with close monitoring of nutritional status [318,322]
Surgical options, such as lung volumereduction surgery, have been used to relieve severe symptoms
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Extension participants continued treatment for an additional 24 weeks (to 104 weeks total) and were transitioned to their maximally tolerated dose of 9 or 12 mg
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