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Int J Clin Pract 2022:4797453 Del Chierico F, Nobili V, Vernocchi P, Russo A, De Stefanis C, Gnani D et al (2017) Gut microbiota profiling of pediatric nonalcoholic fatty liver disease and obese patients unveiled by an integrated meta-omics-based approach
Probiotic use before and throughout the eradication treatment, especially when lasting more than 2 weeks, showed superior outcomes, with the best results observed when probiotics were combined with bismuth quadruple therapy (Shi et al., 2019)
The absence of Phase III human clinical trial data for these compounds is a genuine clinical gap, not a bureaucratic formality
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